Geetanjali serial4/18/2023 Secondary syphilis presents predominantly in mucocutaneous tissues as macular, maculopapular, pustular, and rarely nodular rash after a latent period. Secondary syphilis sometimes presents with only oral mucous patches. The natural course of the disease has been divided into four stages: primary, secondary, latent, and tertiary. Syphilis is a STD caused by spirochaete Treponema pallidum. Leukokeratosis could also be a presentation of secondary syphilis. While being primarily asymptomatic and noncancerous, mystery surrounds its etiology. It can be discerned from lichen planus, white sponge nevus and morsicatio buccarum, erythema multiforme, stomatitis, pemphigus, candidiasis, oral gonorrhea, and other sexually transmitted diseases (STDs) clinically. Leukokeratosis is a white patch or plaque that cannot be characterized clinically or pathologically as any other disease.
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